To Learn Better, Keep the HAT on
نویسندگان
چکیده
Long-lasting memories are known to require new transcription. Recent studies have highlighted a role for epigenetic alterations, including histone acetylation, in regulating gene expression. In this issue of Neuron, Alarcón et al. and Korzus et al. use two different mouse models of Rubinstein-Taybi syndrome to elucidate a role for the histone acetyltransferase activity of CREB binding protein (CBP) in long-term memory and plasticity.
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عنوان ژورنال:
- Neuron
دوره 42 شماره
صفحات -
تاریخ انتشار 2004